Prophylactic Antiemetic Therapy with Ondansetron, Granisetron and Metoclopramide in Patients Undergoing Laparoscopic Cholecystectomy Under GA
نویسندگان
چکیده
The aim of the present study was to compare the antiemetic effect of intravenous Granisetron, Ondansetron & Metoclopramide in a randomized blinded study for prophylaxis of post operative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy under general anaesthesia. 60 patients (ASA I & II) undergoing laparoscopic cholecystectomy under general anaesthesia were randomly allocated into three equal groups (n=20). Emetic episodes in first 24 hours were recorded and compared in different study groups. Results were analyzed. Minimal emetic episodes were observed in early post-operative period (1-12hrs) in patients who had received intravenous granisetron in comparison to ondansetron and metoclopramide. However, after 12 hours emesis free periods were statistically insignificant between group A and B while patients in group C had no antiemetic effect.
منابع مشابه
Post-Laparoscopic Vomiting in Females versus Males: Comparison of Prophylactic Antiemetic Action of Ondansetron versus Metoclopramide
BACKGROUND AND OBJECTIVES The incidence of postoperative vomiting in patients undergoing laparoscopic cholecystectomy is compared in females versus males. The report also compares the prophylactic action of ondansetron versus metoclopramide. METHODS A total of 85 American Society of Anesthesiologists (ASA) I and II patients were enrolled in the study. Patients were divided into two groups acc...
متن کاملA Comparative Study of Intravenous Ondansetron and Granisetron for Prevention of Nausea and Vomiting Following Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is associated with significantly high rate of post operative nausea and vomiting (PONV). This study was designed to compare the effectiveness of Ondansetron with that of Granisetron for prevention of PONV after laparoscopic cholecystectomy. In a randomized, prospective study, 100 patients were selected and randomly divided into two groups of 50 each. Group one recei...
متن کاملThe Comparative Study of Ondansetron and Metoclopramide Effects in Reducing Nausea and Vomiting After Laparoscopic Cholecystectomy.
Postoperative nausea and vomiting (PONV) are one of the most common complications of anesthesia and without prophylactic intervention occurs by about one-third of patients under general anesthesia. The aim of this study was to compare the efficacy of ondansetron and metoclopramide in reducing PONV after laparoscopic cholecystectomy. In this study, 60 patients undergoing laparoscopic cholecystec...
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AIM: To compare qualitatively Metoclopramide, Ondansetron and Granisetron alone and in combination with Dexamethasone in the Prevention of Postoperative Nausea and Vomiting in Day Care Laparoscopic Gynaecological Surgery under General Anaesthesia. METHOD: 180 adult female patients of ASA Grade I and II, BMI <30, aged 18 to 55 years undergoing laparoscopic gynaecological surgery under general an...
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In a randomized, double-blind study, we have compared the prophylactic antiemetic efficacy of ondansetron with that of metoclopramide in 123 patients undergoing general anaesthesia for day-case gynaecological laparoscopic surgery. The patients received either i.v. ondansetron 4 mg or metoclopramide 10 mg immediately before a standard anaesthetic. The number of patients with no nausea or vomitin...
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